
Chronic and neuropathic pain — persistent pain lasting beyond normal healing, including nerve-related pain — is managed at TC Regen by Dr. Megan McGuire, MD, who is double board-certified in Physical Medicine & Rehabilitation and Pain Medicine. TC Regen offers regenerative and interventional pain procedures under Florida's HB 1617 framework at its Naples and Fort Myers locations.
Chronic and neuropathic pain are among the most complex conditions in medicine, often persisting long after an initial injury has healed and, in the case of neuropathic pain, originating from the nervous system itself. At TC Regen, these cases are managed by Dr. Megan McGuire, MD, a physician double board-certified in Physical Medicine & Rehabilitation and Pain Medicine. Care is provided at the Naples and Fort Myers locations using interventional and regenerative procedures within Florida's stem cell therapy framework.
What Are Chronic and Neuropathic Pain?
Chronic pain is generally defined as pain lasting longer than three to six months, persisting beyond the expected period of healing. Neuropathic pain is a specific type that arises from damage to or dysfunction of the nerves themselves, often described as burning, shooting, or tingling. Because pain of this kind can have multiple underlying sources, accurate diagnosis by a pain medicine specialist is essential before any procedure is considered. Dr. McGuire's dual training in PM&R and Pain Medicine allows each case to be evaluated for the source of the pain, not only its symptoms.

Regenerative and Interventional Procedures for Pain
TC Regen offers four categories of regenerative and interventional procedures for chronic and neuropathic pain. Dr. McGuire determines the appropriate option based on the source and type of pain identified during evaluation.Superior resistance against scratches and stone chips
The four procedure categories:
Stem cell therapy — among the pain management indications named in Fla. Stat. § 458.3245, applied where a regenerative pathway is appropriate.
Bone marrow aspirate concentrate (BMAC) — bone marrow concentrate used in regenerative procedures targeting pain-generating tissue.
Platelet-rich plasma (PRP) — platelet concentrate from the patient's own blood, used in soft-tissue and pain-related cases.
Image-guided interventional pain procedures — the core of pain management at TC Regen, using ultrasound or fluoroscopic guidance to reach the precise source of pain.
How TC Regen's Approach Differs
Chronic and neuropathic pain cases are managed by a double board-certified pain medicine physician.
Each case is evaluated for the source of pain, not assigned from a fixed treatment menu.
Regenerative procedures use the patient's own biologic material.
All pain care operates within Florida's HB 1617 framework.
Pain evaluation is available at both the Naples and Fort Myers locations.
Florida HB 1617 and Pain Management
House Bill 1617, codified as Fla. Stat. § 458.3245 and effective July 1, 2025, established a statutory pathway in Florida for non-FDA-approved stem cell therapy across orthopedic, pain management, and wound care indications. Chronic and neuropathic pain fall squarely within the pain management category named in the statute. TC Regen is launching as a regenerative medicine practice operating under this framework, with pain cases managed by Dr. Megan McGuire.
Chronic and neuropathic pain rarely have a single cause, and the right approach depends on identifying the true source. Dr. McGuire evaluates each case individually and matches it to the appropriate procedure. To begin, submit an inquiry and a patient coordinator will contact you within one business day.
